Bioavailability estimation of alternatives

Assessing exposure in absolute or comparative terms necessitates a first-tier comparison of the relative ability of a chemical to enter the living organism. We use proprietary models based on modeling of interactions with biological membranes to assess skin permeation rates and oral bioavailability of chemicals. Furthermore, we enable clients to make quick assessments of bioavailability of new chemicals by tailoring in silico estimation tools to the specific chemical classes of interest.

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ToxFix is a platform for development of predictive tools and design guidelines for reduced toxicity of commercial chemicals. It is managed by DOT (DesigningOutToxicity), a consultancy in Green Chemistry and Toxicology based in Alexandria, Virginia

113 S Columbus St Ste 100

    Alexandria, VA 22314